Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20610091 | 1.00 | MEN1 (0.57) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL20632221 | 0.86 | NPC1 (0.59) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL8815552 | 0.83 | NPC1 (0.57) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL13162953 | 0.82 | MEN1 (0.69) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL30416720 | 0.81 | MEN1 (0.67) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL31019644 | 0.78 | NPC1 (0.65) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL19747532 | 0.76 | MEN1 (0.69) | MEN1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL9975858 | 0.76 | RAB9A (0.83) | MEN1KMT2AL3MBTL1KDM4ENPC1 | |
| SCHEMBL11729468 | 0.76 | NPC1 (0.58) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL27474427 | 0.75 | NPC1 (0.63) | MEN1KMT2ATDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869350-B | Alkynyl compounds, their preparation and their therapeutic use | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |