Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.65 |
| ▸ | RAB9A | P51151 | 12/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27299415 | 0.83 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL11219536 | 0.83 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL4128203 | 0.83 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2980539 | 0.81 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL14985581 | 0.81 | MEN1 (0.67) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL11833252 | 0.80 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL22902863 | 0.80 | RAB9A (0.63) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL3689257 | 0.79 | RAB9A (0.83) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9975858 | 0.79 | RAB9A (0.83) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11223073 | 0.79 | MEN1 (0.75) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300958-A1 | COMPOUNDS AND THE USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BEIJING YOUZHUJU NETWORK TECH CO LTD (CN) | 2024-09-12 | — | — | US | disclosed |
| CN-118619954-A | Compounds, uses and pharmaceutical compositions thereof | 北京有竹居网络技术有限公司 | 2024-09-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300958-A1 | COMPOUNDS AND THE USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | DDR1, DDR2, DDRGK1 | NPC1 1949/4885RAB9A 1595/4885MEN1 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.