SCHEMBL30417

SCHEMBL30417

Cc1cc(C(F)(F)F)nn1CC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
KDM4E B2RXH2 2/20 0.63
POLB P06746 2/20 0.61
TSHR P16473 1/20 0.61
TP53 P04637 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
GAA P10253 3/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 1/20 0.50
HPGD P15428 1/20 0.48
NPSR1 Q6W5P4 1/20 0.46
CCR1 P32246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3580350 0.95 LMNA (0.59) LMNAKDM4EPOLBTSHRTP53
SCHEMBL7797665 0.87 LMNA (0.63) LMNAKDM4EPOLBTSHRTP53
SCHEMBL2220960 0.87 LMNA (0.63) LMNAKDM4EPOLBTSHRTP53
SCHEMBL12516787 0.85 LMNA (0.62) LMNAKDM4EPOLBTSHRTP53
SCHEMBL22095910 0.84 LMNA (0.60) LMNAKDM4EPOLBTSHRTP53
SCHEMBL12883757 0.84 LMNA (0.64) LMNAKDM4EPOLBTSHRTP53
SCHEMBL21780716 0.83 KDM4E (0.74) LMNAKDM4EPOLBTSHRTP53
SCHEMBL29845259 0.83 TP53 (0.66) LMNAKDM4EPOLBTSHRTP53
SCHEMBL1120057 0.81 KDM4E (0.44) LMNAKDM4EPOLBTSHRTP53
SCHEMBL2586705 0.81 LMNA (0.47) LMNAKDM4EPOLBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107619408-A A kind of aminothiazole carboxylic acid derivates and its production and use 南开大学 2018-01-23 CN claimed
CN-104650064-A Aminothiazole carboxylic acid derivatives, and preparation method and application thereof UNIV NANKAI 2015-05-27 CN claimed
CN-122094943-A Novel 1,2, 4-oxadiazoles as fungicides 2026-05-26 CN disclosed
WO-2025133915-A1 COMPOUNDS WHICH BIND TO PNPLA3I148M AND THEIR USE TO TREAT LIVER DISEASES NOVARTIS AG (CH) 2025-06-26 WO disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-115052875-B 4- (4, 5-Dihydroisoxazol-3-yl) thiazol-2-yl) piperidine-thioimine or sulphoxide-imine derivatives and related compounds as fungicides for crop protection PI工业有限公司 2024-07-12 CN disclosed
CN-111662280-B Piperidinyl tetrahydrobenzothiazole oxime ether derivative and application thereof 南开大学 2023-03-03 CN disclosed
EP-4058450-A2 4-(4-(4,5-DIHYDROISOXAZOL-3-YL)THIAZOL-2-YL) PIPERIDINE SULFILIMINE AND SULFOXIMINE DERIVATIVES AND RELATED COMPOUNDS AS FUNGICIDES FOR CROP PROTECTION PI Industries Ltd. (IN) 2022-09-21 EP disclosed
CN-115052875-A 4- (4- (4, 5-dihydroisoxazol-3-yl) thiazol-2-yl) piperidinethimine or sulfoximine derivatives as fungicides for crop protection and related compounds PI工业有限公司 2022-09-13 CN disclosed
EP-4041729-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2022-08-17 EP disclosed
EP-3241829-B1 HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2020-12-23 EP disclosed
EP-2049111-A2 FUNGICIDAL AZOCYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-22 EP disclosed
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
WO-2008091580-A2 FUNGICIDAL AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed
EP-1948649-A2 FUNGICIDAL CARBOXAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-30 EP disclosed
CN-101228156-A Fungicidal carboxamides DU PONT (US) 2008-07-23 CN disclosed
WO-2008013925-A2 FUNGICIDAL AZOCYCLIC AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-31 WO disclosed
WO-2008013622-A2 FUNGICIDAL AZOCYCLIC AMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-31 WO disclosed
WO-2007070433-A2 2-ARYLTHIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS MERCK & CO., INC. (US) 2007-06-21 WO disclosed
WO-2007014290-A2 FUNGICIDAL CARBOXAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-01 WO disclosed