Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417 | 0.87 | LMNA (0.63) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL7797665 | 0.87 | LMNA (0.63) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL12516787 | 0.85 | LMNA (0.62) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL12883757 | 0.84 | LMNA (0.64) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL22095910 | 0.84 | LMNA (0.60) | LMNAKDM4ETP53L3MBTL1POLB | |
| Trifluoroacetic Acid SCHEMBL3580350 | 0.83 | LMNA (0.59) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL21780716 | 0.83 | KDM4E (0.74) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL29845259 | 0.83 | TP53 (0.66) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL3681126 | 0.81 | GRIN2A (0.44) | LMNAKDM4ETP53L3MBTL1POLB | |
| SCHEMBL22892531 | 0.80 | LMNA (0.56) | LMNAKDM4ETP53L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662280-B | Piperidinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2023-03-03 | — | — | CN | disclosed |
| CN-111689927-B | Piperazinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-111689927-A | Piperazinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2020-09-22 | — | — | CN | disclosed |
| CN-111662280-A | Piperidinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2020-09-15 | — | — | CN | disclosed |
| EP-2521450-B1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | DU PONT (US) | 2015-02-25 | — | — | EP | disclosed |
| EP-2121660-B1 | FUNGICIDAL AMIDES | DU PONT (US) | 2014-12-31 | — | — | EP | disclosed |
| WO-2014179144-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-8835427-B2 | Fungicidal heterocyclic compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-09-16 | — | — | US | disclosed |
| WO-2014075874-A1 | MICROBIOCIDAL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-22 | — | — | WO | disclosed |
| US-8586611-B2 | Fungicidal carboxamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-06 | — | — | US | disclosed |
| EP-2521450-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E.I. Du Pont De Nemours And Company (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20110269712-A1 | Fungicidal Carboxamides | BISAHA JOHN JOSEPH | 2011-11-03 | — | — | US | disclosed |
| WO-2011085170-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20100004288-A1 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-01-07 | — | — | US | disclosed |
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269712-A1 | Fungicidal Carboxamides | NAT1, PFAS, CHRM1 | LMNA 2084/4885KDM4E 1416/4885TP53 3715/4885 |
| US-20120309752-A1 | FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, NOX3, CYP1A1 | LMNA 3106/4885KDM4E 1409/4885TP53 4261/4885 |
| US-20100004288-A1 | FUNGICIDAL AMIDES | NAT1, NOX1, Q6ZSR9 | LMNA 3434/4885KDM4E 1591/4885TP53 3952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.