Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041762 | 1.00 | L3MBTL1 (0.54) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL5007090 | 0.88 | ALDH1A1 (0.52) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL5007086 | 0.88 | ALDH1A1 (0.52) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL3033219 | 0.85 | L3MBTL1 (0.54) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL3033224 | 0.85 | L3MBTL1 (0.54) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL601652 | 0.82 | L3MBTL1 (0.59) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL601653 | 0.82 | L3MBTL1 (0.59) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL8069723 | 0.82 | L3MBTL1 (0.59) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL12283486 | 0.79 | L3MBTL1 (0.50) | L3MBTL1TSHRKMT2ALMNAGAA | |
| SCHEMBL14634876 | 0.79 | L3MBTL1 (0.50) | L3MBTL1TSHRKMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | ASTELLAS PHARMA INC (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216798-A1 | FUSED HETEROCYCLES AS LCK INHIBITORS | LCK, ZAP70, FYN | L3MBTL1 918/4885TSHR 974/4885KMT2A 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.