Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | CES1 | P23141 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822696 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL31249634 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL31249635 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL27734126 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL10394740 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL31249638 | 1.00 | CES2 (0.52) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL28750002 | 0.97 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL1349449 | 0.92 | CES2 (0.46) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11787598 | 0.90 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL6903403 | 0.90 | CES2 (0.48) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100172967-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-08 | — | — | US | disclosed |
| US-7696359-B2 | Compound modified with glycerol derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20060280784-A1 | Compound modified with glycerol derivative | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| EP-1666486-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | Kyowa Hakko Kogyo Co., Ltd (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-0285178-B1 | Mannobiose derivatives | MEITO SANGYO KK (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0348942-B1 | LIPID MEMBRANE STRUCTURES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5141751-A | Drug delivery for antitumor agent; mass-reproduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4983725-A | Liposomes with affinity for liver cells | MEITO SANGYO CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0348942-A2 | Lipid membrane structures | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-01-03 | — | — | EP | disclosed |
| EP-0285178-A2 | Mannobiose derivatives | MEITO SANGYO CO., LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060280784-A1 | Compound modified with glycerol derivative | MRGPRX1, MRGPRX2, NPC1L1 | CES2 1069/4885CES1 1747/4885GPR84 181/4885 |
| US-20100172967-A1 | COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE | NPC1L1, SGMS1, SCARB1 | CES2 917/4885CES1 1630/4885GPR84 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.