SCHEMBL30420119

SCHEMBL30420119

CS(=O)(=O)CCc1c[nH]nc1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.36
HCAR2 Q8TDS4 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL948133 0.80 HCAR2 (0.42) HCAR2
SCHEMBL591059 0.77 HCAR2 (0.44) HCAR2
SCHEMBL4878445 0.77 HCAR2 (0.47) HCAR2
SCHEMBL948543 0.75 HCAR2 (0.46) HCAR2
SCHEMBL3044296 0.73 HCAR2 (0.37) HCAR2
SCHEMBL21293440 0.73 HCAR2 (0.35) IKBKBHCAR2
SCHEMBL9956509 0.72 HCAR2 (0.33) HCAR2
SCHEMBL4446514 0.72 HCAR2 (0.33) HCAR2
SCHEMBL1018503 0.72 KDM4E (0.46) HCAR2
SCHEMBL948061 0.71 HCAR2 (0.36) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209664-A Small molecule modulators of IL-17 利奥制药有限公司 2023-06-02 CN disclosed