Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | F3 | P13726 | 2/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042018 | 1.00 | CYP1B1 (0.70) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL3003462 | 0.91 | CYP1B1 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL4970901 | 0.91 | CYP1B1 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL4970910 | 0.91 | CYP1B1 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL3003461 | 0.91 | CYP1B1 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL25201692 | 0.84 | F3 (0.82) | CYP1B1MAPTMEN1ALDH1A1LMNA | |
| SCHEMBL24778812 | 0.84 | XDH (0.64) | CYP1B1MAPTMEN1LMNANFKB1 | |
| SCHEMBL25191745 | 0.84 | F3 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL3762443 | 0.84 | F3 (0.82) | CYP1B1MAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL25285000 | 0.84 | XDH (0.64) | CYP1B1MAPTMEN1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278733-A1 | COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE | NAGASAKI UNIVERSITY (JP) | 2010-11-04 | — | — | US | disclosed |
| EP-2030635-A1 | COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE | Nagasaki University (JP) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278733-A1 | COMPOSITION FOR DIAGNOSIS OF AMYLOID-RELATED DISEASE | APP, FABP7, APBA1 | CYP1B1 3009/4885MAPT 16/4885MEN1 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.