SCHEMBL25201692

SCHEMBL25201692

O=C(/C=C/c1ccc(I)cc1)c1ccc(O)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.82
MAPT P10636 5/20 0.70
RAB9A P51151 4/20 0.70
MAOB P27338 3/20 0.70
MAOA P21397 2/20 0.70
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
CXCL12 P48061 1/20 0.70
POLB P06746 1/20 0.70
KMT2A Q03164 4/20 0.69
MEN1 O00255 3/20 0.69
CYP3A4 P08684 2/20 0.69
HSPD1 P10809 2/20 0.69
HSPE1 P61604 2/20 0.69
CYP1B1 Q16678 2/20 0.69
PKM P14618 1/20 0.69
NFKB1 P19838 1/20 0.69
NFKB2 Q00653 1/20 0.69
RELA Q04206 1/20 0.69
ALDH2 P05091 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25190594 1.00 F3 (0.82) F3MAPTRAB9AMAOBMAOA
4,4'-Dihydroxychalcone SCHEMBL773589 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
4,4'-Dihydroxychalcone SCHEMBL773588 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL10787169 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL25211913 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
4,4'-Dihydroxychalcone SCHEMBL25202156 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL25223420 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL25236411 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL10703657 0.91 F3 (1.00) F3MAPTRAB9AMAOBMAOA
SCHEMBL25285000 0.86 XDH (0.64) F3MAPTRAB9AMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B F3 5/4885MAPT 3297/4885RAB9A 480/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885RAB9A 1327/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 F3 11/4885MAPT 3512/4885RAB9A 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.