Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30420933 | 0.96 | CAPN1 (0.48) | CALCRLNTSR1NTSR2NMUR2NMUR1 | |
| SCHEMBL30420410 | 0.95 | KEAP1 (0.47) | CALCRLNTSR1NTSR2NMUR2NMUR1 | |
| SCHEMBL30335933 | 0.86 | NTSR2 (0.47) | CALCRLNTSR1NTSR2CTSDBACE1 | |
| SCHEMBL29375390 | 0.86 | CALCRL (0.48) | CALCRLKEAP1OPRM1OPRD1CAPN1 | |
| SCHEMBL30432915 | 0.86 | CALCRL (0.50) | CALCRL | |
| SCHEMBL31347657 | 0.85 | CALCRL (0.54) | CALCRLNTSR1NTSR2CTSDBACE1 | |
| SCHEMBL30978825 | 0.85 | BACE1 (0.50) | NTSR1NTSR2NMUR2NMUR1CTSD | |
| SCHEMBL30401176 | 0.85 | SLC6A2 (0.49) | CALCRLNTSR1NTSR2SORT1REN | |
| SCHEMBL30175379 | 0.83 | F2 (0.47) | NTSR1NTSR2SORT1 | |
| SCHEMBL30638815 | 0.82 | SLC6A2 (0.53) | CALCRLNTSR1NTSR2SORT1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116350760-A | Application of CTL epitope peptide derived from new antigen ESR1 or encoding nucleic acid thereof in preparation of medicines | 郑州大学 | 2023-06-30 | — | — | CN | disclosed |