SCHEMBL29375390

SCHEMBL29375390

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nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 6/20 0.48
▸ CAPN1 P07384 2/20 0.45
▸ RAMP3 O60896 5/20 0.44
▸ CALCR P30988 5/20 0.44
▸ RAMP1 O60894 1/20 0.44
▸ KEAP1 Q14145 1/20 0.44
▸ OPRM1 P35372 1/20 0.44
▸ OPRD1 P41143 1/20 0.44
▸ EPHA2 P29317 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30420933 0.89 CAPN1 (0.48) CALCRLCAPN1RAMP3CALCROPRM1
SCHEMBL30099567 0.87 CAPN1 (0.48) CAPN1RAMP3CALCROPRM1OPRD1
SCHEMBL30420755 0.86 CALCRL (0.47) CALCRLCAPN1KEAP1OPRM1OPRD1
SCHEMBL30403555 0.84 CALCRL (0.49) CALCRLCAPN1RAMP3CALCRRAMP1
SCHEMBL30525434 0.84 CALCRL (0.50) CALCRLCAPN1RAMP1OPRM1EPHA2
SCHEMBL30085018 0.84 NTSR1 (0.47) OPRM1OPRD1
SCHEMBL30401176 0.83 SLC6A2 (0.49) CALCRLCAPN1
SCHEMBL31031512 0.83 CAPN1 (0.51) CAPN1RAMP3CALCRKEAP1OPRM1
SCHEMBL30420410 0.83 KEAP1 (0.47) CALCRLCAPN1KEAP1OPRM1OPRD1
SCHEMBL30525445 0.83 CAPN1 (0.53) CALCRLCAPN1RAMP1OPRM1EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302646-A1 BIORESORBABLE, IMPLANTABLE DEVICE HAVING CONTROLLED DRUG DELIVERY SCANLON JOHN JAMES (US) 2025-10-02 — — US disclosed
US-12357480-B2 Bioresorbable, implantable device having controlled drug delivery SCANLON JOHN JAMES (US) 2025-07-15 — — US disclosed
US-20240074882-A1 BIODEGRADABLE ENDOPROSTHESES AND METHODS FOR THEIR FABRICATION ELIXIR MEDICAL CORPORATION (US) 2024-03-07 — — US disclosed
US-20220031482-A1 BIORESORBABLE, IMPLANTABLE DEVICE HAVING CONTROLLED DRUG DELIVERY SCANLON JOHN JAMES (US) 2022-02-03 — — US disclosed
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