Egtazic Acid

Egtazic Acid

SCHEMBL3042159

O=C(O)CN(CCOCCOCCN(CC(=O)O)CC(=O)O)CC(=O)O.[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.95
PMP22 Q01453 2/20 0.95
HSD17B10 Q99714 1/20 0.95
TDP1 Q9NUW8 2/20 0.59
EYA2 O00167 1/20 0.59
APP P05067 1/20 0.59
ACE P12821 1/20 0.59
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
CYP2C19 P33261 1/20 0.56
ADRA1A P35348 1/20 0.56
DRD3 P35462 1/20 0.56
SLC6A3 Q01959 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Egtazic Acid SCHEMBL831877 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL456632 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL456238 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL920203 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
SCHEMBL11684972 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL22901 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL23859106 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL5067266 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL7541607 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL15413556 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743519-B1 Improved method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes BAYER AG (US) 2002-08-28 EP claimed
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP disclosed
EP-4701625-A2 FORMULATION OF THERAPEUTIC AGENTS FOR IMPROVED PERMEATION Vivtex Corporation (US) 2026-03-04 EP disclosed
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP disclosed
CN-119015266-A Water-soluble mixture and method for producing the same 东莞市吉纯生物技术有限公司 2024-11-26 CN disclosed
WO-2024226846-A2 FORMULATION OF THERAPEUTIC AGENTS FOR IMPROVED PERMEATION VIVTEX CORPORATION (US) 2024-10-31 WO disclosed
WO-2024150130-A2 NECROSIS INHIBITOR LINKGEVITY LIMITED (GB) 2024-07-18 WO disclosed
US-7741283-B2 Compositions and methods for inhibiting cell proliferation ST. LOUIS UNIVERSITY (US) 2010-06-22 US disclosed
EP-1836323-A1 METHOD OF PROTECTING AN ANIMAL SKIN PRODUCT FROM METALLOPROTEINASE ACTIVITY BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2007-09-26 EP disclosed
WO-2006060297-A1 METHOD OF PROTECTING AN ANIMAL SKIN PRODUCT FROM METALLOPROTEINASE ACTIVITY BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 2006-06-08 WO disclosed
US-20060112494-A1 Method of protecting an animal skin product from metalloproteinase activity BUCKMAN LABORATORIES INTERNATIONAL, INC. 2006-06-01 US disclosed
US-20050250692-A1 transforming growth factor and insulin like growth factor binding protein 3 as ligands that engage low density lipoprotein receptor-related protein NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-11-10 US disclosed