Egtazic Acid

Egtazic Acid

SCHEMBL456632

O=C(O)CN(CCOCCOCCN(CC(=O)O)CC(=O)O)CC(=O)O.[NaH].[NaH].[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.95
PMP22 Q01453 2/20 0.95
HSD17B10 Q99714 1/20 0.95
TDP1 Q9NUW8 2/20 0.59
EYA2 O00167 1/20 0.59
APP P05067 1/20 0.59
ACE P12821 1/20 0.59
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
CYP2C19 P33261 1/20 0.56
ADRA1A P35348 1/20 0.56
DRD3 P35462 1/20 0.56
SLC6A3 Q01959 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Egtazic Acid SCHEMBL831877 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL456238 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL3042159 1.00 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL920203 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
SCHEMBL11684972 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL22901 0.98 BLM (1.00) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL23859106 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL5067266 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL7541607 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2
Egtazic Acid SCHEMBL15413556 0.95 BLM (0.95) BLMPMP22HSD17B10TDP1EYA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241044-A1 TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2023-08-03 US claimed
EP-4157233-A1 TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES Zydus Lifesciences Limited (IN) 2023-04-05 EP claimed
CN-115666539-A Treatment of psoriasis and skin inflammatory diseases 兹杜斯生命科学有限公司 2023-01-31 CN claimed
WO-2022238745-A1 TOPICAL PHARMACEUTICAL COMPOSITION OF HIF PROLYL HYDROXYLASE INHIBITORS ZYDUS LIFESCIENCES LIMITED (IN) 2022-11-17 WO claimed
WO-2021240454-A1 TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES CADILA HEALTHCARE LIMITED (IN) 2021-12-02 WO claimed
EP-0743519-B1 Improved method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes BAYER AG (US) 2002-08-28 EP claimed
US-20240238189-A1 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. 2024-07-18 US disclosed
US-11992550-B2 Topical skin care formulations comprising plant extracts MARY KAY INC. (US) 2024-05-28 US disclosed
US-20240094222-A1 Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) Biomarkers and Uses Thereof SomaLogic Operating Co, Inc. (US) 2024-03-21 US disclosed
US-20240050357-A1 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. 2024-02-15 US disclosed
US-20240042244-A1 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. 2024-02-08 US disclosed
US-11890369-B2 Topical skin care formulations comprising plant extracts MARY KAY INC. (US) 2024-02-06 US disclosed
WO-2024015486-A1 METHODS FOR SAMPLE QUALITY ASSESSMENT SOMALOGIC OPERATING CO., INC. (US) 2024-01-18 WO disclosed
US-8137714-B2 Compositions comprising docynia delavajy extract and/or Elaeagnus lancelotus extract MARY KAY INC. (US) 2012-03-20 US disclosed
WO-2012033634-A2 TOPICAL SKIN CARE FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. (US) 2012-03-15 WO disclosed
US-20110189322-A1 COMPOSITIONS COMPRISING DOCYNIA DELAVAJY EXTRACT AND/OR ELAEAGNUS LANCELOTUS EXTRACT MARY KAY INC. (US) 2011-08-04 US disclosed
US-20110086116-A1 TOPICAL SKIN FORMULATIONS COMPRISING PLANT EXTRACTS MARY KAY INC. (US) 2011-04-14 US disclosed
US-20110052737-A1 TOPICAL SKIN FORMULATIONS COMPRISING BOTANICAL EXTRACTS MARY KAY INC. (US) 2011-03-03 US disclosed
US-20110044920-A1 TOPICAL SKIN CARE FORMULATIONS MARY KAY INC. (US) 2011-02-24 US disclosed
WO-2010011997-A2 COMPOSITIONS COMPRISING DOCYNIA DELAVAJY EXTRACT AND/OR ELAEAGNUS LANCELOTUS EXTRACT MARY KAY INC. (US) 2010-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241044-A1 TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES P4HA1, PAH, TNF BLM 4828/4885PMP22 1378/4885HSD17B10 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.