SCHEMBL30421978

SCHEMBL30421978

Brc1cccc2c1C=CCC2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16308857 1.00 BCHE (0.32) BCHEACHE
SCHEMBL4445125 0.79 BCL2L1 (0.41)
SCHEMBL30183336 0.78 CA1 (0.32)
SCHEMBL2783384 0.78 CA1 (0.32)
SCHEMBL15129393 0.78 BCHE (0.33) BCHEACHE
SCHEMBL28432571 0.77 CA1 (0.32)
Lithium SCHEMBL29767672 0.77 CA1 (0.32)
SCHEMBL25079074 0.75 DRD2 (0.34) BCHEACHE
SCHEMBL18466666 0.75 BCHE (0.32) BCHEACHE
SCHEMBL5189598 0.75 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118451068-A Tri-fused ring derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2024-08-06 CN disclosed
CN-116194456-A Preparation of heterocyclic compounds as KRAS inhibitors and methods of use thereof 上海科州药物研发有限公司 2023-05-30 CN disclosed