Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKZ | Q13574 | 19/20 | 0.81 |
| ▸ | DGKA | P23743 | 17/20 | 0.81 |
| ▸ | DGKI | O75912 | 3/20 | 0.81 |
| ▸ | DGKG | P49619 | 2/20 | 0.81 |
| ▸ | DGKB | Q9Y6T7 | 2/20 | 0.81 |
| ▸ | DGKK | Q5KSL6 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293186 | 1.00 | DGKZ (0.81) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL23293138 | 0.93 | DGKZ (0.83) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL30616370 | 0.93 | DGKZ (0.83) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL30616441 | 0.92 | DGKZ (0.68) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL23293283 | 0.92 | DGKZ (0.68) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL21830991 | 0.90 | DGKA (1.00) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL29654799 | 0.90 | DGKA (1.00) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL23293507 | 0.88 | DGKA (0.87) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL30616466 | 0.88 | DGKA (0.87) | DGKZDGKADGKIDGKGDGKB | |
| SCHEMBL23293147 | 0.85 | DGKZ (0.81) | DGKZDGKADGKIDGKGDGKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | claimed |
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-3814347-B1 | NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-05-03 | — | — | EP | disclosed |