Ethylene

Ethylene

SCHEMBL3042277

C=C.O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.90
ACLY P53396 2/20 0.34
CA2 P00918 9/20 0.33
CA1 P00915 8/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
LMNA P02545 1/20 0.33
TET2 Q6N021 1/20 0.31
GAA P10253 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL941016 1.00 THRB (0.90) THRBACLYCA2CA1MMP1
Ethylene SCHEMBL940468 1.00 THRB (0.90) THRBACLYCA2CA1MMP1
SCHEMBL24715 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL3368187 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL337248 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL25223581 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL2106472 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL3628434 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL20657170 0.95 THRB (1.00) THRBACLYCA2CA1MMP1
SCHEMBL2637494 0.95 THRB (1.00) THRBACLYCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7811735-B2 Toner, and image forming method, image forming apparatus, and process cartridge using the toner RICOH COMPANY LIMITED (JP) 2010-10-12 US disclosed
US-7785760-B2 Toner and method of preparing the toner RICOH COMPANY LIMITED (JP) 2010-08-31 US disclosed
US-7678522-B2 Toner, and developer, image forming method, image forming apparatus, and process cartridge using the toner RICOH COMPANY LIMITED (JP) 2010-03-16 US disclosed
US-7550242-B2 A binder of a shell/core polymer of polyester shell/addition polymer core formed using an aggregation agent of an inorganic magnesium salt (magnesium chloride); fluorescent X-ray intensity of a peak specific to a Mg-K alpha X-ray of from 3 to 30 Kcps;low temperature fixing; heat resistance; chargability RICOH COMPANY LIMITED (JP) 2009-06-23 US disclosed
US-20080124635-A1 TONER, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE TONER RICOH COMPANY, LTD. (JP) 2008-05-29 US disclosed
US-20070190442-A1 TONER, AND DEVELOPER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE TONER RICOH COMPANY, LTD. (JP) 2007-08-16 US disclosed
US-20070166635-A1 TONER AND METHOD OF PREPARING THE TONER RICOH COMPANY LIMITED (JP) 2007-07-19 US disclosed
US-20060204882-A1 Toner, toner manufacturing method, developer, image forming apparatus, and process cartridge for the image forming apparatus RICOH COMPANY LIMITED (JP) 2006-09-14 US disclosed