Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040022 | 0.85 | KCNA3 (0.45) | KCNA3KDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL27676789 | 0.80 | KCNA3 (0.46) | KCNA3KDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL3041687 | 0.79 | ALDH1A1 (0.47) | KCNA3KDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL3045327 | 0.75 | TACR1 (0.41) | HSD17B10ATMTSHR | |
| SCHEMBL3041470 | 0.75 | CREBBP (0.50) | KCNA3KDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL12204834 | 0.73 | BDKRB1 (0.44) | ALDH1A1POLBMAPTATM | |
| SCHEMBL2516752 | 0.71 | BDKRB1 (0.54) | KCNA3ALDH1A1GAAPOLBMAPT | |
| SCHEMBL4468979 | 0.71 | HTT (0.48) | KDM4EALDH1A1POLBMAPTHTT | |
| SCHEMBL68113 | 0.71 | KDM4E (0.50) | KDM4EHIF1AHSD17B10ALDH1A1GLA | |
| SCHEMBL2516421 | 0.70 | BDKRB1 (0.44) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | 4SC AG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-7276606-B2 | Phenantridine analogues and uses thereof | 4SC AG (DE) | 2007-10-02 | — | — | US | disclosed |
| EP-1740548-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| EP-1652841-A1 | Novel phenantridine analogues and their use as inhibitors of hyperproliferation of T cells and/or keratinocytes | Switch Biotech Aktiengesellschaft (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20050282801-A1 | Novel phenantridine analogues and uses thereof | SWITCH BIOTECH AG (DE) | 2005-12-22 | — | — | US | disclosed |
| WO-2005105752-A1 | NOVEL PHENANTRIDINE ANALOGUES AND THEIR USES AS INHIBITORS OF HYPERPROLIFERATION OF T CELLS AND/OR KERATINOCYTES | 4SC AG (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | P2RX4, P2RX5, CLIC4 | KCNA3 52/4885KDM4E 2178/4885HIF1A 2740/4885 |
| US-20050282801-A1 | Novel phenantridine analogues and uses thereof | P2RX4, P2RX5, CLIC4 | KCNA3 52/4885KDM4E 2178/4885HIF1A 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.