SCHEMBL30423432

SCHEMBL30423432

CC(C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.58
▸ UTS2R Q9UKP6 1/20 0.56
▸ ECE1 P42892 10/20 0.55
▸ GHSR Q92847 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31632618 0.94 ACE (0.55) ACEUTS2RECE1GHSR
SCHEMBL30898976 0.94 ACE (0.55) ACEUTS2RECE1GHSR
SCHEMBL29496441 0.91 GHSR (0.65) GHSR
SCHEMBL29496564 0.91 GHSR (0.65) GHSR
SCHEMBL30130571 0.90 GHSR (0.59) ACEUTS2RECE1GHSR
SCHEMBL30422428 0.90 ACE (0.62) ACEECE1GHSR
SCHEMBL30130563 0.90 GHSR (0.59) ACEUTS2RECE1GHSR
SCHEMBL31619560 0.90 IL23R (0.59) UTS2RGHSR
SCHEMBL31619561 0.90 IL23R (0.59) UTS2RGHSR
SCHEMBL29972966 0.90 IL23R (0.59) UTS2RGHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3603648-B1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID SHIONOGI & CO (JP) 2025-09-17 — — EP disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid FABP1, POLRMT, SREBF1 ACE 1569/4885UTS2R 3115/4885ECE1 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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