Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253857 | 1.00 | TPH1 (0.33) | TPH1EP300 | |
| SCHEMBL30424565 | 1.00 | TPH1 (0.33) | TPH1EP300 | |
| SCHEMBL24253750 | 1.00 | TPH1 (0.33) | TPH1EP300 | |
| SCHEMBL30494535 | 0.93 | TPH1 (0.32) | TPH1EP300 | |
| SCHEMBL24253559 | 0.93 | TPH1 (0.32) | TPH1EP300 | |
| SCHEMBL24253867 | 0.88 | — | — | |
| SCHEMBL30423918 | 0.88 | EP300 (0.30) | EP300 | |
| SCHEMBL24253860 | 0.88 | EP300 (0.30) | EP300 | |
| SCHEMBL24253864 | 0.86 | — | — | |
| SCHEMBL30424524 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | claimed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| EP-4196478-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Novartis AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-116157404-A | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 诺华股份有限公司 | 2023-05-23 | — | — | CN | disclosed |