SCHEMBL30423765

SCHEMBL30423765

[Li]c1ccccc1-c1cc(C(C)(C)CC)cc(C(C)(C)CC)c1OCOC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 3/20 0.34
ALDH1A1 P00352 1/20 0.34
RXRA P19793 5/20 0.33
PPARG P37231 5/20 0.33
RARG P13631 4/20 0.33
MAPT P10636 2/20 0.32
HTT P42858 2/20 0.32
UBE2N P61088 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22320312 1.00 MAPK1 (0.38) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL22334484 0.86 MAPK1 (0.39) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL22320329 0.85 MAPK1 (0.38) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL22356571 0.84 MAPK1 (0.38) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL28629392 0.82 MAPK1 (0.40) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL30423244 0.73 RXRA (0.36) MAPK1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL22320302 0.73 RXRA (0.36) MAPK1SMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL26081392 0.69 RXRA (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL22320162 0.68 RXRA (0.36) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL28629390 0.68 MAPK1 (0.33) MAPK1SMN1; SMN2NPC1LMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423742-B Bis (arylphenoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed