SCHEMBL22320302

SCHEMBL22320302

CCC(C)(C)c1cc(Br)c(OCOC)c(C(C)(C)CC)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.36
PPARG P37231 5/20 0.36
RARG P13631 4/20 0.36
MEN1 O00255 3/20 0.35
MAPK1 P28482 3/20 0.35
KMT2A Q03164 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
ALDH1A1 P00352 2/20 0.35
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 2/20 0.32
UBE2N P61088 2/20 0.32
GLA P06280 1/20 0.32
MITF O75030 1/20 0.32
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423244 1.00 RXRA (0.36) RXRAPPARGRARGMEN1MAPK1
SCHEMBL22320329 0.82 MAPK1 (0.38) RXRAPPARGRARGMEN1MAPK1
SCHEMBL6033258 0.80 ALDH1A1 (0.36) RXRAPPARGRARGALDH1A1
SCHEMBL22356571 0.76 MAPK1 (0.38) RXRAPPARGRARGMEN1MAPK1
SCHEMBL31405203 0.75
SCHEMBL23014691 0.75 ALDH1A1 (0.44) MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1
SCHEMBL22334484 0.74 MAPK1 (0.39) RXRAPPARGRARGMEN1MAPK1
SCHEMBL22320312 0.73 MAPK1 (0.38) RXRAPPARGRARGMEN1MAPK1
SCHEMBL30423765 0.73 MAPK1 (0.38) RXRAPPARGRARGMEN1MAPK1
SCHEMBL26260717 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423742-B Bis (arylphenoxide) lewis base catalysts and methods thereof 埃克森美孚化学专利公司 2023-05-05 CN disclosed
EP-3924395-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2021-12-22 EP disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-21 US disclosed
CN-113423742-A Bis (arylphenolate) lewis base catalysts and processes thereof 埃克森美孚化学专利公司 2021-09-21 CN disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
WO-2020167824-A1 B!S(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-08-20 WO disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed
US-20200254431-A1 BIS(ARYL PHENOLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. 2020-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11203654-B2 Bis(aryl phenolate) lewis base catalysts and methods thereof PHKB, TYR, ELL RXRA 1370/4885PPARG 432/4885RARG 2857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.