Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15541699 | 0.89 | SLC9A1 (0.50) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| Trifluoroacetic Acid SCHEMBL15541698 | 0.89 | SLC9A1 (0.50) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL29047805 | 0.87 | HTR2A (0.54) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL24193339 | 0.87 | HTR2A (0.54) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL24193337 | 0.87 | HTR2A (0.54) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| Trifluoroacetic Acid SCHEMBL3045297 | 0.76 | KDM1A (0.51) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL7090511 | 0.73 | HTR2C (0.62) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL7654609 | 0.73 | HTR2C (0.62) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL5521413 | 0.73 | HTR2C (0.62) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 | |
| SCHEMBL15542074 | 0.73 | HTR2C (0.62) | SLC9A1HTR2AHTR2CHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157154-A | Plasma kallikrein inhibitors | 默沙东有限责任公司 | 2023-05-23 | — | — | CN | disclosed |