SCHEMBL30424015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27812271	0.87	AKT1 (0.55)	AKT2AKT1RPS6KA3PIM1PIM3
	SCHEMBL28941664	0.86	AKT2 (0.87)	AKT2AKT1PIM1CHEK1CHEK2
	SCHEMBL15606681	0.86	AKT2 (0.87)	AKT2AKT1PIM1CHEK1CHEK2
	SCHEMBL23804742	0.86	AKT2 (0.59)	AKT2AKT1CHEK1ROCK2
	SCHEMBL20597906	0.86	AKT2 (0.59)	AKT2AKT1RPS6KA3PIM1PIM3
	SCHEMBL17980346	0.86	NT5E (0.59)	AKT2AKT1RPS6KA3CHEK1NT5E
	SCHEMBL980068	0.86	CHEK1 (0.59)	AKT2AKT1RPS6KA3CHEK1ROCK2
	SCHEMBL22861241	0.86	AKT2 (0.59)	AKT2AKT1RPS6KA3PIM1PIM3
	SCHEMBL4582269	0.86	AKT2 (0.59)	AKT2AKT1RPS6KA3PIM1PIM3
	SCHEMBL3089533	0.86	AKT1 (0.59)	AKT2AKT1RPS6KA3PIM1PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.