SCHEMBL3042452

SCHEMBL3042452

CCCC[Si](C)(C)OC(C)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491818 0.91 SPHK1 (0.36) SPHK1
SCHEMBL23093225 0.81 LMNA (0.30)
SCHEMBL2582808 0.80 TSHR (0.39)
SCHEMBL11805520 0.79 TSHR (0.35) SPHK1
SCHEMBL29655537 0.79
SCHEMBL8896852 0.78
SCHEMBL25405283 0.77
SCHEMBL6538580 0.77
SCHEMBL11805641 0.75
SCHEMBL8792932 0.75 CA2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093657-B Wear-resistant PVC material and application thereof 广东亮丰达实业有限公司 2024-04-30 CN disclosed
EP-3166950-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF Cipla Limited (IN) 2017-05-17 EP disclosed
EP-3137074-A1 PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, COMPOSITIONS, AND USES RELATED THERETO Emory University (US) 2017-03-08 EP disclosed
WO-2016020664-A1 PROCESS FOR THE SYNTHESIS OF EVEROLIMUS AND INTERMEDIATES THEREOF CIPLA LIMITED (IN) 2016-02-11 WO disclosed
WO-2015167825-A1 PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, COMPOSITIONS, AND USES RELATED THERETO EMORY UNIVERSITY (US) 2015-11-05 WO disclosed
WO-2010127272-A2 HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES CONCERT PHARMACEUTICALS, INC. (US) 2010-11-04 WO disclosed
EP-0722447-A1 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-07-24 EP disclosed
WO-1995010520-A1 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-04-20 WO disclosed