Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263770 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL636847 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTMAPTCA12CA1 | |
| Bromide SCHEMBL637005 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTMAPTCA12CA1 | |
| SCHEMBL7262939 | 0.82 | CA12 (0.37) | SMN1; SMN2HTTMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL28754080 | 0.73 | MAPT (0.38) | SMN1; SMN2HTTMAPTTSHRBCL2 | |
| Hydrochloric Acid SCHEMBL6702513 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL10708206 | 0.73 | HDAC8 (0.40) | SMN1; SMN2HTTMAPTCA12CA1 | |
| SCHEMBL26186710 | 0.72 | CA12 (0.43) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL25530877 | 0.72 | CA12 (0.37) | SMN1; SMN2HTTMAPTCA12CA1 | |
| SCHEMBL26806792 | 0.71 | CA12 (0.46) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040166-A1 | PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海瑞宏迪医药有限公司 | 2025-02-27 | — | — | WO | disclosed |
| WO-2023093905-A1 | AADC/GDNF POLYNUCLEOTIDE, AND USE THEREOF IN TREATING PARKINSON'S DISEASE | 上海瑞宏迪医药有限公司 | 2023-06-01 | — | — | WO | disclosed |