Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16276909 | 0.73 | TRPV1 (0.34) | HTTKDM4E | |
| SCHEMBL25405006 | 0.73 | — | — | |
| SCHEMBL27974704 | 0.73 | NOTUM (0.35) | KDM4E | |
| SCHEMBL2044973 | 0.70 | — | — | |
| SCHEMBL29615194 | 0.70 | CASP1 (0.38) | HTTHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL21100986 | 0.70 | SSTR4 (0.30) | — | |
| SCHEMBL6033831 | 0.69 | MKNK1 (0.51) | — | |
| SCHEMBL25399307 | 0.68 | — | — | |
| SCHEMBL3516550 | 0.68 | GLA (0.40) | NOS3NOS2KDM4EPOLB | |
| SCHEMBL1025834 | 0.68 | HTT (0.46) | HTTHSD17B10NOS3NOS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451068-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| EP-4182308-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | disclosed |