Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689253 | 0.83 | NOS3 (0.39) | HTTHSD17B10KDM4EL3MBTL1TLR7 | |
| SCHEMBL28513854 | 0.81 | PDE10A (0.41) | HTTHSD17B10KDM4EL3MBTL1KMT2A | |
| SCHEMBL30615592 | 0.79 | HTT (0.39) | HTTHSD17B10KDM4EL3MBTL1TLR7 | |
| SCHEMBL29581438 | 0.79 | MAPT (0.47) | HTTHSD17B10KDM4EL3MBTL1KMT2A | |
| SCHEMBL21463674 | 0.79 | HTT (0.39) | HTTHSD17B10KDM4EL3MBTL1TLR7 | |
| SCHEMBL5178183 | 0.78 | HTT (0.41) | HTTHSD17B10KDM4EL3MBTL1TLR7 | |
| SCHEMBL7803270 | 0.77 | NOS3 (0.41) | HTTKDM4ENOS3NOS2NOS1 | |
| SCHEMBL10515301 | 0.77 | ALDH1A1 (0.39) | HTTKDM4ENOS3NOS2NOS1 | |
| SCHEMBL30113073 | 0.77 | HTT (0.46) | HTTHSD17B10KDM4EL3MBTL1TLR7 | |
| SCHEMBL16914429 | 0.74 | PSMD14 (0.45) | HTTHSD17B10KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | claimed |
| CN-102977009-B | A kind of synthetic method of 2-trifluoromethyl-3-fluorine pyridine | Ao Sainuo bio tech ltd, Hangzhou (CN) | 2015-07-29 | — | — | CN | claimed |
| CN-102977009-A | Synthesizing method of 2-trifluoromethyl-3-fluoropyridin | HANGZHOU ALLSINO CHEMICAL CO LTD | 2013-03-20 | — | — | CN | claimed |
| EP-1252889-B1 | REMEDIES OR PREVENTIVES FOR PULMONARY INSUFFICIENCY CONTAINING DIAMINOTRIFLUOROMETHYLPYRIDINE DERIVATIVES | ISHIHARA SANGYO KAISHA (JP) | 2006-08-09 | — | — | EP | claimed |
| US-20030109551-A1 | Remedies or preventives for pulmonary insufficiency containing diaminotrifluoromethylpyridne derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-06-12 | — | — | US | claimed |
| EP-1252889-A1 | REMEDIES OR PREVENTIVES FOR PULMONARY INSUFFICIENCY CONTAINING DIAMINOTRIFLUOROMETHYLPYRIDINE DERIVATIVES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2002-10-30 | — | — | EP | claimed |
| EP-0228846-B1 | AMINO-TRIFLUOROMETHYLPYRIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-22 | — | — | EP | claimed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | claimed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | claimed |
| JP-62155259-A | — | — | None | — | — | JP | disclosed |
| JP-6247934-A | — | — | None | — | — | JP | disclosed |
| EP-4727932-A1 | SMALL MOLECULE LIGANDS AND APTAMERS | MeiraGTx Gene Regulation Limited (GB) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098047-A1 | Anti-Giardial Compounds | COMMW SCIENT IND RES ORG (AU) | 2026-04-09 | — | — | US | disclosed |
| EP-4720060-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2026-04-08 | — | — | EP | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| JP-S62155259-A | AMINOTRIFLUOROMETHYLPYRIDINE AND ITS PRODUCTION | ISHIHARA SANGYO KAISHA LTD | 1987-07-10 | — | — | JP | disclosed |
| EP-0206951-A2 | Process for the perfluoroalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109551-A1 | Remedies or preventives for pulmonary insufficiency containing diaminotrifluoromethylpyridne derivatives | CBR1, CBR3, WDR1 | HTT 4289/4885HSD17B10 2161/4885KDM4E 3997/4885 |
| US-20260098047-A1 | Anti-Giardial Compounds | GNAO1, GPR6, MGAT3 | HTT 3585/4885HSD17B10 2925/4885KDM4E 3910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.