Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305409 | 0.71 | KMT2A (0.39) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL30822359 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2NPSR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22948213 | 0.69 | ALDH1A1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29556777 | 0.69 | ALDH1A1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL25388763 | 0.67 | SCN10A (0.42) | — | |
| SCHEMBL7841369 | 0.66 | NPSR1 (0.42) | KDM4ESMN1; SMN2NPSR1ALDH1A1HTT | |
| SCHEMBL12248189 | 0.66 | NPSR1 (0.47) | KDM4ESMN1; SMN2NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL18124754 | 0.66 | ATM (0.47) | KDM4ESMN1; SMN2NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL11367624 | 0.66 | KDM4E (0.67) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL25390661 | 0.65 | SCN10A (0.41) | KDM4ESMN1; SMN2ALDH1A1HTTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |