Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329324 | 1.00 | DPP4 (0.45) | DPP4TSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL2185042 | 0.88 | DPP4 (0.42) | DPP4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL23535454 | 0.85 | TSHR (0.60) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL30427170 | 0.85 | TSHR (0.60) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL17150208 | 0.84 | DPP4 (0.47) | DPP4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2249995 | 0.84 | TSHR (0.46) | DPP4TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3079030 | 0.84 | MEN1 (0.51) | TSHRMEN1KMT2ARAB9AHSP90AA1 | |
| SCHEMBL3079283 | 0.81 | JMJD6 (0.56) | TSHRALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL24746841 | 0.81 | ALDH1A1 (0.49) | DPP4TSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL18341514 | 0.81 | NPC1 (0.46) | DPP4TSHRHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118786117-A | Heterocyclic amides and methods of use thereof | 亚根达医疗公司 | 2024-10-15 | — | — | CN | disclosed |
| EP-4433457-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | Rgenta Therapeutics, Inc. (US) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023092098-A1 | HETEROCYCLIC AMIDES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |