Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21873426 | 1.00 | GRM2 (0.40) | GRM2MEN1PABPC1KMT2AADORA2A | |
| SCHEMBL30427587 | 0.90 | IGFBP5 (0.43) | GRM2MEN1PABPC1KMT2AADORA2A | |
| SCHEMBL21873443 | 0.90 | IGFBP5 (0.43) | GRM2MEN1PABPC1KMT2AADORA2A | |
| SCHEMBL21873492 | 0.84 | ALDH1A1 (0.43) | GRM2KMT2AADORA2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL30427986 | 0.84 | ALDH1A1 (0.43) | GRM2KMT2AADORA2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL21935353 | 0.82 | CHRM1 (0.47) | KMT2AADORA2A | |
| SCHEMBL21873464 | 0.81 | CHRM1 (0.44) | — | |
| SCHEMBL21873436 | 0.80 | BRD4 (0.37) | — | |
| SCHEMBL21873398 | 0.80 | CHRM1 (0.48) | GRM2CSF1R | |
| SCHEMBL31668977 | 0.79 | CHRM1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709401-B | Heterocyclic compounds | 武田药品工业株式会社 | 2023-06-13 | — | — | CN | disclosed |