Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.63 |
| ▸ | BCL2 | P10415 | 10/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.61 |
| ▸ | BCL2A1 | Q16548 | 7/20 | 0.61 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532050 | 0.77 | BCL2L1 (0.76) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL352771 | 0.77 | BCL2L1 (1.00) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL2532052 | 0.76 | BCL2L1 (1.00) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL353855 | 0.76 | BCL2L1 (1.00) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL19420198 | 0.75 | BCL2L1 (0.94) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL10112868 | 0.74 | BCL2L1 (0.95) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL2622283 | 0.73 | BCL2L1 (0.60) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL19425625 | 0.72 | BCL2L1 (0.90) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL10113185 | 0.72 | BCL2L1 (0.90) | BCL2L1BCL2MCL1BCL2A1BAK1 | |
| SCHEMBL11566552 | 0.71 | LMNA (0.55) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581660-B1 | NICHE TARGETING OF QUIESCENT CANCER STEM CELLS | UNIV CALIFORNIA (US) | 2023-06-07 | — | — | EP | claimed |
| EP-3581660-B1 | NICHE TARGETING OF QUIESCENT CANCER STEM CELLS | UNIV CALIFORNIA (US) | 2023-06-07 | — | — | EP | disclosed |