Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061359 | 0.88 | KDM4E (0.51) | LMNAKDM4EGLACYP3A4MAPT | |
| SCHEMBL7541652 | 0.80 | RAB9A (0.52) | LMNAKDM4EGLACYP3A4MAPT | |
| SCHEMBL1133182 | 0.75 | KDM4E (0.53) | LMNAKDM4EGLACYP3A4MAPT | |
| SCHEMBL11872629 | 0.75 | MAPT (0.56) | LMNAKDM4ECYP3A4MAPTMEN1 | |
| SCHEMBL10423387 | 0.73 | KDM4E (0.55) | LMNAKDM4EGLACYP3A4MAPT | |
| SCHEMBL8965058 | 0.73 | CYP3A4 (0.63) | LMNACYP3A4ACHEMAPTMEN1 | |
| SCHEMBL16010609 | 0.73 | LMNA (0.53) | LMNAKDM4EGLAMAPTALDH1A1 | |
| SCHEMBL7533334 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPK1GAA | |
| SCHEMBL11566548 | 0.71 | LMNA (1.00) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL30428669 | 0.71 | BCL2L1 (0.63) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |