SCHEMBL3042896

SCHEMBL3042896

CCCOc1ccc2cc(C(=O)c3ccccc3)c(=O)oc2c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.83
RAB9A P51151 3/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
KDM4E B2RXH2 3/20 0.72
NPC1 O15118 2/20 0.72
POLB P06746 1/20 0.72
MAOB P27338 5/20 0.61
SLC16A3 O15427 2/20 0.61
HPGD P15428 2/20 0.60
MIF P14174 1/20 0.60
PKM P14618 2/20 0.59
MAOA P21397 2/20 0.59
GLA P06280 1/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
MAPK1 P28482 1/20 0.59
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HDAC1 Q13547 1/20 0.55
MEN1 O00255 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16944053 0.86 ALDH1A1 (0.72) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL4400321 0.86 ALDH1A1 (0.72) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL20752257 0.86 RAB9A (0.79) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL16944055 0.86 ALDH1A1 (0.68) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL15616856 0.86 ALDH1A1 (0.78) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL15616846 0.84 ALDH1A1 (0.80) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL16944050 0.84 ALDH1A1 (0.69) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL16674827 0.84 MAOB (0.69) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL51978 0.84 ALDH1A1 (1.00) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL16944060 0.84 ALDH1A1 (0.69) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1624920-B1 BALLOON WITH IMPROVED RETENTION BOSTON SCIENT LTD (BB) 2007-12-26 EP claimed
EP-1624920-A1 BALLOON WITH IMPROVED RETENTION Boston Scientific Limited (BB) 2006-02-15 EP claimed
WO-2004105851-A1 BALLOON WITH IMPROVED RETENTION BOSTON SCIENTIFIC LIMITED (BB) 2004-12-09 WO claimed
US-20040236398-A1 Catheter balloon with improved retention BOSTON SCIENTIFIC SCIMED, INC. 2004-11-25 US claimed
US-7776078-B2 Catheter balloon with improved retention BOSTON SCIENTFIC SCIMED, INC. (US) 2010-08-17 US disclosed
EP-1624920-B1 BALLOON WITH IMPROVED RETENTION BOSTON SCIENT LTD (BB) 2007-12-26 EP disclosed
EP-1624920-A1 BALLOON WITH IMPROVED RETENTION Boston Scientific Limited (BB) 2006-02-15 EP disclosed
WO-2004105851-A1 BALLOON WITH IMPROVED RETENTION BOSTON SCIENTIFIC LIMITED (BB) 2004-12-09 WO disclosed
US-20040236398-A1 Catheter balloon with improved retention BOSTON SCIENTIFIC SCIMED, INC. 2004-11-25 US disclosed
US-6294593-B1 COMBINING HOST POLYMER WITH GUEST CROSSLINIKING AGENT; EXPOSING COMBINED HOST POLYMER AND GUEST CROSSLINKING AGENT TO ELECTRIC FIELD TO POLE SECOND ORDER NONLINEAR OPTICAL COMPONENT OF POLYMER; EXPOSING TO ELECTROMAGNETIC RADIATION UNIVERSITY OF MASSACHUSETTS LOWELL 2001-09-25 US disclosed
US-5484821-A PHOTOCROSSLINKED UNIVERSITY OF LOWELL (US) 1996-01-16 US disclosed
US-5290824-A Stilbene, azomethine and disazo dyes, polyvinyl cinnamate, polyvinylstyryl acrylate or polyvinyl chalcone polymer matrix UNIVERSITY OF LOWELL (US) 1994-03-01 US disclosed
US-5223356-A Holography UNIVERSITY OF LOWELL (US) 1993-06-29 US disclosed
US-5112881-A Chromogens reacted into crosslinkable polymer, three-dimensional network UNIVERSITY OF LOWELL (US) 1992-05-12 US disclosed