Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | MIF | P14174 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | STK17B | O94768 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078524 | 0.86 | TOP1 (0.66) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL30429737 | 0.83 | ACHE (0.68) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL30428321 | 0.83 | TOP1 (0.58) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL21046410 | 0.79 | STK17B (0.76) | MEN1ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29935565 | 0.79 | STK17B (0.76) | MEN1ALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22625287 | 0.77 | CSNK2A2 (0.59) | MIFMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4267530 | 0.76 | TOP1 (0.76) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL4267528 | 0.76 | TOP1 (0.76) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL14078677 | 0.76 | MIF (0.70) | TOP1TOP2AMIFMEN1ALDH1A1 | |
| SCHEMBL4261091 | 0.75 | TOP1 (0.75) | TOP1TOP2AMIFMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |