Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TOP1 | P11387 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30429323 | 0.83 | TOP1 (0.59) | ACHEMAOBTOP1TOP2AMIF | |
| SCHEMBL1078524 | 0.82 | TOP1 (0.66) | ACHEMAOBTOP1TOP2AMIF | |
| 4'-Methoxy-Aurone SCHEMBL19462849 | 0.81 | ACHE (1.00) | ACHEMAOBMAPTKMT2AKDM4E | |
| 4'-Methoxy-Aurone SCHEMBL14099569 | 0.81 | ACHE (1.00) | ACHEMAOBMAPTKMT2AKDM4E | |
| SCHEMBL12696418 | 0.78 | MAPT (0.68) | MAOBTOP1TOP2AMAPTLMNA | |
| SCHEMBL1702750 | 0.77 | TRPA1 (0.53) | ACHEMAPTGFERHPGDMETAP1 | |
| SCHEMBL4909985 | 0.75 | SOS1 (0.65) | ACHEMAOBMIFMAPTNPSR1 | |
| SCHEMBL4345256 | 0.75 | SOS1 (0.65) | ACHEMAOBMIFMAPTNPSR1 | |
| SCHEMBL4262064 | 0.75 | TOP1 (0.54) | ACHEMAOBTOP1TOP2AMIF | |
| SCHEMBL4262061 | 0.75 | TOP1 (0.54) | ACHEMAOBTOP1TOP2AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |