Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632412 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1LMNAPDCD1CD274 | |
| SCHEMBL14302077 | 0.83 | HDAC1 (0.52) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4633855 | 0.83 | F10 (0.41) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28540549 | 0.81 | SMN1; SMN2 (0.54) | ALDH1A1LMNAKMT2AMEN1NPC1 | |
| SCHEMBL17342166 | 0.81 | HTT (0.54) | KDM4EALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL16080074 | 0.77 | USP2 (0.40) | ALDH1A1L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL22380 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAL3MBTL1GLA | |
| SCHEMBL29395460 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAL3MBTL1GLA | |
| SCHEMBL10213140 | 0.77 | KMT2A (0.40) | ALDH1A1L3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL28551538 | 0.77 | USP2 (0.40) | ALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110719908-B | Process for preparing 3, 4-dichloro-N- (2-cyanophenyl) -5-isothiazolecarboxamide | 拜耳股份公司 | 2023-05-26 | — | — | CN | claimed |
| EP-3774749-B1 | METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE | BAYER AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| CN-110719908-B | Process for preparing 3, 4-dichloro-N- (2-cyanophenyl) -5-isothiazolecarboxamide | 拜耳股份公司 | 2023-05-26 | — | — | CN | disclosed |