Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1085042 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL25151051 | 0.87 | CYP3A4 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL18786786 | 0.86 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24773237 | 0.86 | CYP3A4 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL22689984 | 0.85 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL1710208 | 0.85 | KDM4E (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL1085064 | 0.84 | POLB (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL25343847 | 0.84 | KDM4E (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL24175026 | 0.84 | CYP3A4 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL14660349 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134022-B | ATR inhibitors and uses thereof | 上海德琪医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-116554151-B | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-116554151-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4175948-A1 | ATR INHIBITORS AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-05-10 | — | — | EP | disclosed |