Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978357 | 0.84 | ALDH1A1 (0.41) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL12844283 | 0.78 | SMN1; SMN2 (0.42) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL17788487 | 0.72 | MAPT (0.40) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL6760580 | 0.69 | SMN1; SMN2 (0.44) | LMNATP53ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL13100036 | 0.69 | RAB9A (0.42) | LMNATP53ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10864189 | 0.69 | RAB9A (0.43) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL3320936 | 0.68 | SMN1; SMN2 (0.41) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL22459222 | 0.66 | NR2F2 (0.50) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL23400598 | 0.66 | HPGD (0.38) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL12650452 | 0.66 | TTR (0.41) | MAPTPOLBLMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025164-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | disclosed |