Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357159 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL30433135 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4GAATDP1 | |
| SCHEMBL8519995 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL16369640 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL3059008 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL1373524 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL21834461 | 0.74 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL29451885 | 0.73 | MCL1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Potassium Ion SCHEMBL28557203 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| SCHEMBL525582 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |