Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111922 | 0.80 | S1PR4 (0.50) | ALDH1A1CYP3A4ALOX15TDP1HTT | |
| SCHEMBL2983082 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL30433361 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ALOX15TDP1MAPT | |
| SCHEMBL8536343 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL28757542 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL10582813 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL7026429 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL2979886 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| Potassium Ion SCHEMBL31252976 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 | |
| SCHEMBL2967553 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118613484-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-116209476-A | Antifolate linker-drug and antibody-drug conjugates | 拜奥迪斯私人有限公司 | 2023-06-02 | — | — | CN | disclosed |