Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 7/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 7/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144604 | 0.72 | DYRK1A (0.38) | — | |
| SCHEMBL27870413 | 0.71 | XDH (0.58) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL27870411 | 0.71 | CFTR (0.49) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL27886646 | 0.71 | CFTR (0.49) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL3027244 | 0.71 | MAPKAPK2 (0.59) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL3032900 | 0.71 | MAPKAPK2 (0.47) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL27886637 | 0.70 | PI4KA (0.64) | CFTRXDHCDK1CCNB1CCNE1 | |
| SCHEMBL1165308 | 0.70 | DYRK1A (0.36) | — | |
| SCHEMBL28960375 | 0.69 | XDH (0.62) | XDHCDK1CCNB1CCNE1CDK2 | |
| SCHEMBL28230093 | 0.69 | CDK1 (0.48) | CFTRXDHCDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |