SCHEMBL304348

SCHEMBL304348

CCCCCCCCc1c(C(F)(F)F)nc2ncnn2c1N

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MBOAT4 Q96T53 19/20 0.50
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5225182 1.00 MBOAT4 (0.50) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL5228485 1.00 MBOAT4 (0.50) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL17646445 0.89 MBOAT4 (0.44) MBOAT4
SCHEMBL5227195 0.84 MBOAT4 (0.49) MBOAT4
SCHEMBL5402153 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL3122488 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL3133063 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL3130141 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL303749 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2
SCHEMBL4921904 0.83 GAA (0.45) MBOAT4GAAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
EP-1909579-B1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2015-10-07 EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 US claimed
EP-2066177-B1 FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2014-12-24 EP claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 US claimed
US-20140155263-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines BASF SE (DE) 2014-06-05 US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 US claimed
US-8461077-B2 Combinations of active substances BASF SE (DE) 2013-06-11 US claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
EP-2552213-A2 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2013-02-06 EP claimed
US-20080234295-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines BASF AKTIENGELSELLSCHAFT (DE) 2008-09-25 US claimed
WO-2008095913-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-14 WO claimed
WO-2008092759-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2008-08-07 WO claimed
WO-2008092836-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2008-08-07 WO claimed
EP-1909579-A1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2008-04-16 EP claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
US-7307172-B2 7-amino triazolopyrimidines for controlling harmful fungi BASF AKTIENGESELLSCHAFT (DE) 2007-12-11 US claimed
EP-1414302-B1 7-AMINO TRIAZOLOPYRIMIDINES FOR CONTROLLING HARMFUL FUNGI BASF AG (DE) 2007-03-21 EP claimed
WO-2007012598-A1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF AKTIENGESELLSCHAFT (DE) 2007-02-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS MBOAT4 3142/4885GAA 187/4885HTT 968/4885
US-20140155263-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines DDT, STS, ARSA MBOAT4 4718/4885GAA 1285/4885HTT 3552/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS MBOAT4 3539/4885GAA 615/4885HTT 1511/4885
US-20080234295-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines DDT, STS, ARSA MBOAT4 4718/4885GAA 1285/4885HTT 3552/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP MBOAT4 4595/4885GAA 327/4885HTT 1671/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT MBOAT4 3224/4885GAA 270/4885HTT 1859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.