Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447446 | 1.00 | SNCA (0.40) | SNCATDP1ATMALDH1A1MAPT | |
| SCHEMBL21061886 | 0.86 | TSHR (0.42) | ALDH1A1PTPN1ACP1CDC25BMAOA | |
| SCHEMBL21061683 | 0.85 | KMT2A (0.41) | ATMALDH1A1MAPTMAPK1PTPN1 | |
| SCHEMBL28445030 | 0.85 | PTPN1 (0.37) | ALDH1A1MAPTPTPN1ACP1CDC25B | |
| SCHEMBL21061949 | 0.85 | HPD (0.41) | TDP1ALDH1A1MAPTMAPK1CYP1A2 | |
| SCHEMBL29500904 | 0.85 | HPD (0.41) | TDP1ALDH1A1MAPTMAPK1CYP1A2 | |
| SCHEMBL21062120 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1PTPN1MAOA | |
| SCHEMBL29500903 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1PTPN1MAOA | |
| SCHEMBL8307611 | 0.83 | PTPN1 (0.41) | ALDH1A1MAPTPTPN1ACP1CDC25B | |
| SCHEMBL29500921 | 0.81 | TDP1 (0.40) | SNCATDP1ATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479813-B | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2023-03-21 | — | — | CN | disclosed |