Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224059 | 1.00 | MAOB (0.56) | MAOBMAP4K4CLK2DYRK1ASRPK1 | |
| SCHEMBL25536494 | 0.89 | MAOB (0.52) | MAOBMAP4K4CLK2DYRK1ASRPK1 | |
| SCHEMBL30435799 | 0.82 | CSF1R (0.50) | NPC1MAPTRAB9ASMN1; SMN2CSF1R | |
| SCHEMBL25232996 | 0.82 | CSF1R (0.50) | NPC1MAPTRAB9ASMN1; SMN2CSF1R | |
| SCHEMBL30436723 | 0.77 | CSF1R (0.60) | NPC1MAPTRAB9ASMN1; SMN2CSF1R | |
| SCHEMBL25239044 | 0.77 | CSF1R (0.60) | NPC1MAPTRAB9ASMN1; SMN2CSF1R | |
| SCHEMBL25232229 | 0.77 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2CSF1RALDH1A1 | |
| SCHEMBL30436982 | 0.77 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2CSF1RALDH1A1 | |
| SCHEMBL1752546 | 0.74 | MAPK14 (0.71) | MAOB | |
| SCHEMBL25245214 | 0.74 | RAB9A (0.66) | NPC1MAPTRAB9ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096304-A1 | ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-06-01 | — | — | WO | claimed |
| WO-2023096304-A1 | ISOXAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-06-01 | — | — | WO | disclosed |