Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.66 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.66 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611362 | 0.90 | CYP11B2 (0.67) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL30437002 | 0.87 | PPARG (0.62) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL21055977 | 0.87 | PPARG (0.62) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL31171360 | 0.86 | CYP11B2 (0.61) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL13162545 | 0.85 | CYP11B2 (0.64) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL21056024 | 0.85 | PPARG (0.72) | CYP11B2CYP11B1BRAFSGMS2PPARG | |
| SCHEMBL13162335 | 0.85 | BRAF (0.76) | CYP11B2CYP11B1BRAFSGMS2PPARG | |
| SCHEMBL18161358 | 0.85 | GRM5 (0.73) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL21056003 | 0.84 | PPARG (0.78) | GRM5CYP11B2CYP11B1BRAFSGMS2 | |
| SCHEMBL30436387 | 0.84 | PPARG (0.78) | GRM5CYP11B2CYP11B1BRAFSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498694-A1 | NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2019-06-19 | — | — | EP | claimed |
| WO-2024211969-A1 | PPARG MODULATORS | Setonix Pharmaceuticals Pty Ltd (AU) | 2024-10-17 | — | — | WO | disclosed |
| EP-3498694-A1 | NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2019-06-19 | — | — | EP | disclosed |