Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437026 | 0.78 | MKNK1 (0.50) | MKNK1MKNK2CYP11B2 | |
| SCHEMBL30436871 | 0.78 | JAK3 (0.51) | CYP11B2ACACBACACAJAK1JAK3 | |
| SCHEMBL30436844 | 0.77 | NR4A2 (0.49) | NR4A2ACACBACACA | |
| SCHEMBL21955797 | 0.75 | PARP1 (0.51) | MKNK2NR4A2 | |
| SCHEMBL18615799 | 0.74 | CHEK2 (0.65) | MKNK1MKNK2CHEK2CYP11B2 | |
| SCHEMBL30436722 | 0.73 | ALK (0.41) | ACACBACACAJAK1JAK3 | |
| SCHEMBL11156328 | 0.73 | MKNK1 (0.63) | MKNK1MKNK2CHEK2CYP11B2CYP2A6 | |
| SCHEMBL30437354 | 0.72 | GRIN2B (0.46) | ACACBACACA | |
| SCHEMBL26405275 | 0.72 | ALDH1A1 (0.54) | MKNK1MKNK2 | |
| SCHEMBL24296515 | 0.71 | NR4A2 (0.76) | MKNK1MKNK2NR4A2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102549-A | 5-aldehyde heterocyclic amide compound and application thereof | 暨南大学 | 2023-05-12 | — | — | CN | claimed |