Bromide

Bromide

SCHEMBL3043706

C=C(C)C(=O)NCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.48
HTT P42858 2/20 0.47
HSP90AA1 P07900 1/20 0.43
RAD52 P43351 1/20 0.43
EPHX1 P07099 4/20 0.42
KMT2A Q03164 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
PLA2G2A P14555 1/20 0.40
PLA2G4A P47712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL2371393 1.00 DNM1 (0.48) DNM1HTTHSP90AA1RAD52EPHX1
SCHEMBL5713236 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
SCHEMBL290065 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
SCHEMBL16798891 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
SCHEMBL13766065 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
SCHEMBL15579565 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
SCHEMBL16799240 0.98 HTT (0.48) DNM1HTTEPHX1KMT2AZDHHC20
Hydrochloric Acid SCHEMBL1977630 0.97 HTT (0.47) DNM1HTTHSP90AA1RAD52EPHX1
Hydrochloric Acid SCHEMBL7106835 0.97 HTT (0.47) DNM1HTTHSP90AA1RAD52EPHX1
Hydrochloric Acid SCHEMBL10383927 0.97 HTT (0.47) DNM1HTTHSP90AA1RAD52EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11407928-B2 Organophilic clay based drilling fluids containing Gemini surfactant and polyacrylamide KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-08-09 US claimed
US-20200325381-A1 ORGANOPHILIC CLAY BASED DRILLING FLUIDS CONTAINING GEMINI SURFACTANT AND POLYACRYLAMIDE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-10-15 US claimed
EP-1732960-B1 NOVEL HIGH MOLECULAR WEIGHT ASSOCIATIVE AMPHOTERIC POLYMERS AND USES THEREOF SPCM SA (FR) 2018-12-05 EP claimed
EP-2834320-B1 NEW AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING METHOD IMPLEMENTING THE FLUID SPCM SA (FR) 2018-02-21 EP claimed
US-9249352-B2 Aqueous fracturing fluid composition and fracturing process using the composition S.P.C.M. SA (FR) 2016-02-02 US claimed
US-20130255954-A1 NOVEL AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING PROCESS USING THE COMPOSITION S.P.C.M. SA (FR) 2013-10-03 US claimed
US-7700702-B2 High molecular weight associative amphoteric polymers and uses thereof SNF S.A.S. (FR) 2010-04-20 US claimed
US-11613686-B2 Associative copolymers with hydrophobic quaternized (meth)acrylamide and (meth)acrylic acid derivatives BASF SE (DE) 2023-03-28 US disclosed
US-11407928-B2 Organophilic clay based drilling fluids containing Gemini surfactant and polyacrylamide KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2022-08-09 US disclosed
CN-109070025-B Method and device for preparing aqueous polymer solution 巴斯夫欧洲公司 2022-06-07 CN disclosed
US-20210230331-A1 ASSOCIATIVE COPOLYMERS WITH HYDROPHOBIC QUATERNIZED (METH)ACRYLAMIDE AND (METH)ACRYLIC ACID DERIVATIVES BASF SE (DE) 2021-07-29 US disclosed
US-11015106-B2 Reusable high performance water based drilling fluids WEATHERFORD TECHNOLOGY HOLDINGS, LLC (US) 2021-05-25 US disclosed
EP-3802725-A1 ASSOCIATIVE COPOLYMERS WITH HYDROPHOBIC QUATERNIZED (METH)ACRYLAMIDE AND (METH)ACRYLIC ACID DERIVATIVES BASF SE (DE) 2021-04-14 EP disclosed
US-9249352-B2 Aqueous fracturing fluid composition and fracturing process using the composition S.P.C.M. SA (FR) 2016-02-02 US disclosed
WO-2015052644-A1 REUSABLE HIGH PERFORMANCE WATER BASED DRILLING FLUIDS CLEARWATER INTERNATIONAL, LLC (US) 2015-04-16 WO disclosed
US-20150096808-A1 REUSABLE HIGH PERFORMANCE WATER BASED WELLS FARGO BANK, NATIONAL ASSOCIATION 2015-04-09 US disclosed
WO-2015024865-A1 STABILISED COMPOSITIONS CONTAINING ACRYLAMIDE POLYMERS, AND METHOD FOR THE TERTIARY PRODUCTION OF CRUDE OIL USING SAID COMPOSITIONS BASF SE (DE) 2015-02-26 WO disclosed
US-20130255954-A1 NOVEL AQUEOUS FRACTURING FLUID COMPOSITION AND FRACTURING PROCESS USING THE COMPOSITION S.P.C.M. SA (FR) 2013-10-03 US disclosed
US-7700702-B2 High molecular weight associative amphoteric polymers and uses thereof SNF S.A.S. (FR) 2010-04-20 US disclosed
US-20070287815-A1 Novel High Molecular Weight Associative Amphoteric Polymers And Uses Thereof SNF SAS (FR) 2007-12-13 US disclosed