Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917312 | 1.00 | PRSS1 (0.55) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL28875159 | 0.94 | MAPT (0.56) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL28411160 | 0.92 | MAPT (0.58) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL5373240 | 0.91 | MAPT (0.59) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL17466183 | 0.88 | TDP1 (0.65) | MAPTALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL14770230 | 0.88 | MAPT (0.59) | MAPTALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL29049879 | 0.87 | LMNA (0.59) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL3680561 | 0.87 | PRSS1 (0.72) | PRSS1PRSS2PRSS3ALDH1A1LMNA | |
| SCHEMBL6264048 | 0.87 | PRSS1 (0.68) | PRSS1PRSS2PRSS3MAPTALDH1A1 | |
| SCHEMBL9620202 | 0.87 | PRSS1 (0.72) | PRSS1PRSS2PRSS3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |