Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917312 | 0.94 | PRSS1 (0.55) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL30437460 | 0.94 | PRSS1 (0.55) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL7864534 | 0.92 | MAPT (0.61) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL14770230 | 0.90 | MAPT (0.59) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL8956804 | 0.88 | MAPT (0.56) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL5373240 | 0.87 | MAPT (0.59) | MAPTALDH1A1LMNACYP3A4CA2 | |
| SCHEMBL570998 | 0.86 | ALDH1A1 (0.66) | MAPTALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL28411160 | 0.86 | MAPT (0.58) | MAPTALDH1A1LMNACYP3A4TDP1 | |
| SCHEMBL30112129 | 0.86 | ALDH1A1 (0.70) | ALDH1A1LMNACYP3A4CA2TDP1 | |
| SCHEMBL206454 | 0.86 | ALDH1A1 (0.70) | ALDH1A1LMNACYP3A4CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072858-A | Indole derivatives as glucagon receptor antagonist | 詹森药业有限公司 | 2019-07-30 | — | — | CN | disclosed |