Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24970800 | 0.91 | LMNA (0.48) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL20810903 | 0.91 | LMNA (0.48) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL20810791 | 0.86 | LMNA (0.48) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL24972739 | 0.86 | LMNA (0.48) | LMNADNM1ALDH1A1TSHRTHRB | |
| SCHEMBL23031750 | 0.83 | LMNA (0.42) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL24972697 | 0.82 | LMNA (0.45) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL11211294 | 0.82 | ALDH1A1 (0.54) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL8856280 | 0.82 | ALDH1A1 (0.54) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL18978505 | 0.82 | LMNA (0.54) | LMNADNM1ALDH1A1TDP1TSHR | |
| SCHEMBL28037565 | 0.82 | LMNA (0.54) | LMNADNM1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120198-B | Lipid compound with glycerol skeleton, lipid carrier based on lipid compound, nucleic acid lipid nanoparticle composition and pharmaceutical preparation | 苏州科锐迈德生物医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-116120198-A | Lipid compound with glycerol skeleton, lipid carrier based on lipid compound, nucleic acid lipid nanoparticle composition and pharmaceutical preparation | 苏州科锐迈德生物医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |